The combined OCT/SLO (optical coherence tomography and scanning laser ophthalmoscope) instrument for imaging the eye was invented at Kent in 1998 by Adrian Podoleanu and David Jackson.
- Optical mapping apparatus with adjustable depth resolution
The United States Patent 5975697 · Filed: 11/25/1998 · Published: 11/02/1999.
- Combined Optical Coherence Tomograph and Scanning Laser Ophthalmoscope, A. Gh. Podoleanu and D. A. Jackson, Electronics Letters, Vol. 34, No. 11, (1998), pp. 1088-1090.
- Noise Analysis of a Combined Optical Coherence Tomograph and a Confocal Scanning Ophthalmoscope, A. Gh. Podoleanu, D. A. Jackson, Appl. Optics, Vol. 38, (1999), No. 10, pp. 2116 – 2127.
Our first OCT/SLO was an en-face system, with the OCT channel operating based on en-facetime domain OCT.
After 2002, spectral domain OCT technology took off, and the SLO channel was then paired sequentially with a spectral domain OCT channel. A system based on this principle was commercialised by Optos Plc., based on the patent:
- Optical imaging apparatus with a spectral detector, United States Patent 7649629 B2 · Filed: 10/05/2007 · Published: 01/19/2010
The acronym OCT/SLO lives on, referring to spectral domain OCT which is now so fast that an en face fundus image can be created in real time from the OCT volume. Several groups have reported generation of these fundus images to guide conventional B-scan spectral domain OCT imaging, and these systems are now also described as OCT/SLO.