Optical coherence tomography (OCT) is an emerging imaging technique, which offers a non-invasive way to evaluate scattering tissues. Although ophthalmic OCT has become the standard-of-care in the United States and Europe and is being adapted as the standard-of-care in interventional cardiology and preclinical cancer research, it is still limited in terms of imaging speed. By applying the frequency multiplexing approach we expand the capabilities of time domain OCT by performing the imaging using multiple imaging channels simultaneously. The method bridges the gap between time domain and spectral domain OCT. The technique is extremely versatile as it can be used for multiple depth imaging or polarization sensitive imaging as well as for combinations of mentioned modalities.
We believe that the idea of using frequency division multiplexing in optical imaging will be interesting not only for scientists working in the fields of optical imaging and optical sensing but for medical scientists as well, who are looking for alternative methods to observe motile organs and tissues.
Publications
Mantas Zurauskas, Adrian Bradu, Adrian Gh. Podoleanu, “Frequency multiplexed long range swept source optical coherence tomography,” Biomed. Opt. Express 4, 778 (2013)
http://dx.doi.org/10.1364/BOE.4.000778
Mantas Zurauskas, John Rogers, and Adrian Podoleanu, “Simultaneous multiple-depths en-face optical coherence tomography using multiple signal excitation of acousto-optic deflectors,” Opt. Express 21, 1925-1936 (2013)
http://dx.doi.org/10.1364/OE.21.001925
Selected conference proceedings
Mantas Zurauskas, Adrian Podoleanu. ” A versatile frequency domain multiplexer for optical coherence tomography,” Frontiers in Optics. OSA, (2012).
http://dx.doi.org/10.1117/12.2035004
Mantas Zurauskas, John Rogers, and Adrian G. Podoleanu, “Polarization sensitive en face optical coherence tomography using multichannel acousto-optic deflectors,” Paper 8571-89, ISPDI 2013, SPIE (2013)
http://dx.doi.org/10.1117/12.2006089
Mantas Zurauskas, John Rogers, Adrian Podoleanu. “Multiple-depth simultaneous en-face optical coherence tomography imaging,” Frontiers in Optics. OSA, (2012).
http://dx.doi.org/10.1364/FIO.2012.FTu1C.2