The output from a joint OCT/SLO system, with the SLO image on the left and the OCT on the right. The top of the optic nerve, then the RPE and at the end the lamina cribrosa are seen in the OCT image. In the SLO image, these are visible all the time. The animation is made up from forty 3 mm x 3 mm images collected from the optic nerve in 20 seconds, with a total exploration depth of 1.5 mm.

The combined OCT/SLO (optical coherence tomography and scanning laser opthalmoscope) instrument for imaging the eye was invented in 1998 by Adrian Podoleanu and David Jackson, and is described in the following patents and papers:


The assembly of a unique compact opthalmological imaging system capable en-face OCT/SLO as well as longitudinal SLO (collaboration with Ophthalmic Technology Inc Canada)

Our first OCT/SLO was an en-face system, where the OCT channel operates based on en-face time domain OCT. After 2002, spectral domain OCT technology took off, and the SLO channel was then paired sequentially with a spectral domain OCT channel. Such a system is now sold by Optos Plc., based on the patent:

Optical imaging apparatus with spectral detector, United States Patent 7649629 B2 · Filed: 10/05/2007 · Published: 01/19/2010

The acronym OCT/SLO lives on meaning now different formats of OCT. Spectral domain OCT technology is now so fast, that a fundus image can be created using spectral domain OCT. Several groups have now reported generation of a fundus type image to guide the B-scan imaging based by the spectral domain OCT, and labelled their instruments as OCT/SLO.



Key publications on the OCT/SLO in the Applied Optics Group